Schematic illustration of oxytocin (OT) and dopamine (DA) neurocircuitry involved in pair bonding, bonding disruption, and social buffering in prairie voles. OT receptor densities are illustrated in each of the OT projection areas including the prefrontal cortex (PFC), nucleus accumbens (NAcc), lateral septum (LS), bed nucleus of the stria terminalis (BST), medial preoptic area (MPA), amygdala (Amyg), and ventral tegmental area (VTA), while both DA D1-type and D2-type receptors are present in the NAcc, PFC, and caudate putamen (CP).