. Author manuscript; available in PMC: 2016 Oct 20.

Published in final edited form as: Diabetologia. 2013 Dec 11;57(3):455–462. doi: 10.1007/s00125-013-3134-3

Table 4.

Relationship between weight loss and changes in pancreatic beta cell function and meal-associated profile

Variable	Placebo		Liraglutide

	Standardised β coefficient^a	p value	Standardised β coefficient^a	p value
GGIT
Δ ISR AUC	0.52	0.01	−0.54	0.59
Δ Slope	−0.15	0.47	0.18	0.43
MMTT
Δ Glucose AUC	0.41	0.05	0.14	0.57
Δ Insulin AUC	0.41	0.04	0.02	0.93
Δ NEFA AUC	0.11	0.58	0.02	0.93

Standarised coefficients are shown from the regression analysis

Dependent variables are listed in the table; the independent variable was percentage weight loss. Analysis was also adjusted for age, sex and ethnicity

ISR, insulin secretion rate