Table 5. Mean C-ACTc scores and mean differences in C-ACTc scores between patients with and without an EPAC in the prior period of 4 weeks.
| Clinical event | No. of EPACs/% visits | EPAC | No EPAC |
Differences in C-ACTc score |
|
|---|---|---|---|---|---|
| C-ACTc Mean (95% CI) | C-ACTc Mean (95% CI) | Mean (95% CI) | P-valuea | ||
| EPAC | 353/46 | 8.6 (8.3, 8.8) | 9.0 (8.7, 9.3) | 0.38 (0.14,0.63) | <0.01 |
|
EPAC components | |||||
| Decrease in PEFR | 263/34 | 8.8 (8.5, 9.1) | 8.9 (8.6, 9.2) | 0.08 (−0.20, 0.36) | 0.57 |
| Increase in rescue medication use | 169/22 | 8.2 (7.8, 8.6) | 9.0 (8.8, 9.3) | 0.85 (0.52, 1.18) | <0.001 |
| Systemic corticosteroids | 80/10 | 8.2 (7.8, 8.7) | 8.9 (8.6, 9.2) | 0.68 (0.29, 1.07) | <0.01 |
| Urgent careb | 53/7 | 8.3 (7.7, 8.8) | 8.9 (8.6, 9.2) | 0.64 (0.13, 1.15) | 0.03 |
Abbreviations: CI, confidence interval; C-ACT, childhood Asthma-Control Test; EPAC, episodes of poor asthma control; PEFR, peak expiratory flow rate.
a
P values are based on linear regression models of the effect of the occurrence of an EPAC on the change in score at the next visit and accounted for correlation among repeated measures.
b
Urgent care is defined as an ‘urgent unscheduled healthcare contact for asthma’ and includes emergency department, hospital, clinic, or doctor’s office visits.