Table 2.

Relative mRNA levels of inflammasome components in PBMC normalized to ACTB/GAPDH/B2M. Data are derived from 62 male and 38 female patients.

Target genes	Male Median [range]	Female Median [range]	P- Valuea
AIM2	1.03 [0.14–9.42]	0.73 [0.04–1.72]	0.00009
NLRP3	1.59 [0.42–9.90]	0.58 [0.01–4.88]	0.000038
ASC (PYCARD)	2.89 [0.75–13.74]	1.24 [0.39–6.56]	0.000004
CASP1	1.06 [0.41–4.47]	0.67 [0.19–2.25]	0.000004
CASP5	1.22 [0.00–5.58]	0.18 [0.01–2.01]	< 0.000001
IL1B	2.34 [0.07–45.06]	0.25 [0.00–10.67]	< 0.000001

^aData was analyzed using the Mann Whitney U test.