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Effect of YD0171 on mitochondrial and nuclear DNA integrity in HCT116 cells. Cells were treated with YD0171 (100, 300 or 1 mmol/L) or AOAA (100, 300 or 1 mmol/L) for 48 h, followed by LA-PCR assays. *p < 0.05 and **p < 0.01 indicate significant reduction in DNA integrity compared with control. Data are shown as mean ± SEM; n = 6.
