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Effect of YD0171 on the transsulfuration pathway metabolites in HCT116 cells. Cells were treated with YD0171 (1 mmol/L) or AOAA (1 mmol/L) for 24 h, followed by metabolomic analysis. The left panel shows the relative position of the various measured metabolites in the transsulfuration pathway. *p < 0.05 and **p < 0.01 indicate significant effect of the test compounds compared with control. Data are shown as mean ± SEM values of n = 3.
