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Effect of covalent modifications of AOAA on recombinant CBS activity in vitro.
| Compound | Structure | CBS activity (% of control) at 100 μmol/L |
|---|---|---|
| AOAA |  |
10 ± 3 |
| YD0135 |  |
114 ± 5 |
| YD0151 |  |
91 ± 2 |
| YD0154 |  |
74 ± 5 |
| YD0163 |  |
163 ± 12 |
| YD0164 |  |
83 ± 9 |
| YD0177 |  |
92 ± 3 |
| YD0196 |  |
108 ± 11 |
| YD0197 |  |
94 ± 3 |
