Figure 7.

TO reverses increased protein synthesis pathways in the DH lung. The processes downregulated in DHTO compared with DH involved protein synthesis, protein trafficking and ribosomal biogenesis. The ribosomal biogenesis KEGG pathway demonstrates reduced expression of many ribosomal genes in DHTO / DH (32,33). Differentially expressed genes are colored, with the left half color indicating expression change in DHTO versus Control, and right half DH versus control. Red boxes indicate upregulated genes, green boxes downregulated genes, and gray boxes expressed genes without different mRNA levels. White boxes indicate genes that did not meet our inclusion criteria.