Table 1. . Whole blood 450K methylation datasets that were used to create the reference library and analyzed for variations.
| Study (year) | Title | Sample size | Study accession ID | Ref. |
|---|---|---|---|---|
| Kulis et al. (2015) |
Human B-cell differentiation methylation |
35 |
EGAD00010000716 |
[14] |
| Lee et al. (2013) |
A global DNA methylation and gene expression analysis of early human B-cell development |
22 |
GSE45461 |
[15] |
| Reinius et al. (2012) |
Differential DNA methylation in purified human blood cells |
60 |
GSE35069 |
[8] |
| Wiencke et al. (2015) |
Activated NKs, dendritics, Tregs |
|
|
[16] |
|
Whole blood methylation | ||||
| Ali et al. (2015) |
An epigenetic map of age-associated autosomal loci in northern European families at high risk for the metabolic syndrome |
192 |
GSE40279 |
[6] |
| Liu et al. (2013) |
Differential DNA methylation in rheumatoid arthritis |
689 |
GSE42861 |
[3] |
| Hannum et al. (2012) | Genome-wide methylation profiles reveal quantitative views of human aging rates | 656 | GSE40279 | [2] |
NK: Natural killer cell.