Table 3.

Mutually adjusted hazard ratios from the Cox proportional hazard regression

		With treatment adjustment		Without treatment adjustment
		HR (95% CI)	p-value	HR (95% CI)	p-value
HPV Status
HPV16-positive		Ref		Ref
Non-HPV16-positive		1.75(0.91, 3.37)	0.096	1.92(1.03, 3.60)	0.041
HPV-negative		1.44(0.85, 2.46)	0.177	1.38(0.81, 2.34)	0.236
Sex
Male		Ref		Ref
Female		0.80(0.47, 1.37)	0.413	0.78(0.45, 1.35)	0.376
Race
White		Ref		Ref
Black		1.65(1.00, 2.72)	0.051	1.87(1.13, 3.09)	0.015
Smoking
<10 Pack-years		Ref		Ref
≥10 Pack-years		1.75(1.02, 3.02)	0.043	1.82(1.07, 3.10)	0.028
Alcohol
<1 drink/week		Ref		Ref
≥1 drink/week		1.04(0.49, 2.22)	0.911	1.11(0.52, 2.38)	0.787
Age		1.02(1.00, 1.04)	0.114	1.02(1.00, 1.04)	0.100
T Classification
T1–T2		Ref
T3–T4		1.85(1.24, 2.75)	0.002
N Classification
N0		Ref
N+		1.08(0.64, 1.83)	0.765
Treatment
Single modality		Ref
Multiple modality		1.00(0.53, 1.90)	0.99