Figure 1.

Effect of a single IT injection of salicylate 100 µg/10 µl, Tropisetron 100 µg/10 µl and 150 µg/10 µl on mechanical allodynia. Data are expressed as mean ± SEM of 50% withdrawal threshold. The mean 50% withdrawal threshold is significantly increased following administration of salicylate (100 µg/10 µl), and Tropisetron (150 µg/10 µl) compared to saline-treated animals and before injection. * statistical difference with saline-treated groups (P < 0.01), $ statistical defference with pre-treatment (P < 0.001). #, statistical difference with control groups (p < 0.001).