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. 2016 Oct 14;9:357–366. doi: 10.2147/CCID.S111999

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© 2016 Jensen et al. This work is published and licensed by Dove Medical Press Limited

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The effects of WSEM on human dermal fibroblasts are shown as the average ± standard deviation of triplicate cultures.

Notes: WSEM showed a mild but significant increase in the proliferation of dermal fibroblasts (A). In addition, WSEM-treated dermal fibroblasts showed an increase in the production of elastin (B) and collagen (C). The increases in elastin and collagen levels in the dermal fibroblast cultures were not due to the content of those compounds in WSEM, since the 5 g/L dose of WSEM showed similar levels as the negative control (medium alone) at or below 6 ng/mL (data not shown). Statistical significance (P<0.05) is calculated compared to untreated cell cultures, and where significance was reached indicated by *.

Abbreviations: TGF, transforming growth factor; WSEM, water-soluble egg membrane.