Table 4. Association of plasma endothelin level with polymorphic variants of K198N, C122T, C70G, G231A.
| K198N | ||||
|---|---|---|---|---|
| ET level |
TT |
GG |
GT |
P value |
| NTG |
1.4 (0.97–9.82) |
1.24(0.78–2.02) |
1.32(0.88–3.29) |
0.850 |
| HTG |
11.78(3.13–20.43) |
1.87(0.87–3.85) |
1.05(0.76–2.0) |
0.059 |
| C1222T | ||||
| ET level |
TT |
CC |
CT |
|
| NTG |
4.62(1.02–15.84) |
0.96(0.66–1.48) |
1.27(0.86–1.92) |
0.034 |
| HTG |
3.85(1.05–9.57) |
1.46(0.79–2.88) |
1.87(0.77–2.70) |
0.410 |
| C70G | ||||
| ET level |
GG |
CC |
CG |
|
| NTG |
0.96(0.64–1.47) |
1.92(1.02–9.16) |
1.27(0.79–2.2) |
0.048 |
| HTG |
1.53(0.88–2.86) |
1.22(0.76–7.43) |
1.92(0.95–4.71) |
0.690 |
| G231A | ||||
| ET level |
GG |
AA |
GA |
|
| NTG |
1.06(0.75–2.02) |
15.84(0.34–19.72) |
1.32(0.914–1.76) |
0.580 |
| HTG | 1.87(0.98–3.85) | 19.31(0.2–20.43) | 1.36(0.76–2.88) | 0.081 |