Table 1. Correlation of gene-expression with immunohistochemistry for HLA.
mAb HCA2 | mAb HC10 | mAb Tal.1B5 | ||||
---|---|---|---|---|---|---|
Gene-expression (Illumina) | (HLA-A) | (HLA-B/C) | (HLA-DR) | |||
r | p | r | p | r | p | |
HLA-A | .434 | 0.02 | .545 | 0.003 | .161 | 0.41 |
HLA-B | .488 | 0.01 | .609 | 0.001 | .286 | 0.14 |
B2M | .346 | 0.07 | .508 | 0.006 | .279 | 0.15 |
HLA-DR | .242 | 0.21 | .332 | 0.08 | .225 | 0.25 |
HLA-DQ | .301 | 0.12 | .400 | 0.04 | .172 | 0.38 |
Correlation of HLA gene-expression, as determined with the Illumina array, with the results of HLA immunohistochemical staining in 28 cases of UM. r = two-tailed Spearman correlation coefficient. p = p-value.