Table 1.
Characteristics and grouping of the study population
| Characteristics | Cases | Controls | P-value | COPD with PH | COPD without PH | P-value |
|---|---|---|---|---|---|---|
| n | 513 | 506 | 150 | 363 | ||
| Age, years (mean±SD) | 68.02±11.21 | 56.49±9.43 | <0.001 | 70.03±12.37 | 67.19±10.60 | 0.190 |
| Male, n% | 432 (84.21) | 414 (81.82) | 0.318 | 126 (84.00) | 306 (84.30) | 1.000 |
| Pack-years | 43.08±21.71 | 39.45±19.58 | <0.001 | 41.93±21.65 | 40.47±23.51 | 0.467 |
| BMI, kg/m2 | 23.75±2.57 | 24.18±2.48 | 0.575 | 24.16±2.27 | 23.57±2.69 | 0.051 |
| FEV1 %, predicted | 36.77±16.94 | 95.77±12.98 | <0.001 | 35.67±16.10 | 37.23±18.64 | 0.138 |
| FEV1/FVC | 0.43±0.19 | 0.81±0.96 | <0.001 | 0.43±0.15 | 0.45±0.26 | 0.004 |
| GOLD classification | Level 3 | Level 3 | Level 3 | |||
| PASP, mmHg | 49.64±14.25 | 25.37±5.73 | <0.001 |
Note: P<0.05 indicates statistical significance.
Abbreviations: BMI, body mass index; GOLD, Global initiative for chronic Obstructive Lung Disease; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; PASP, pulmonary artery systolic pressure; PH, pulmonary hypertension.