. 2016 Oct 14;11:2563–2571. doi: 10.2147/COPD.S109026

Table 2.

Basic characteristics of SNPs in the enrolled population

SNPs	Chromosomes	Position	Gene	Allele	Risk of COPD				Risk of COPD with PH
SNPs	Chromosomes	Position	Gene	Allele	HWE-P	OR	95% CI	Allele, P-value	HWE-P	OR	95% CI	Allele, P-value
rs2362290	2q37.1	233916724	TRPM8	AG	0.061	1.03	0.85–1.24	0.781	0.291	0.8	0.60–1.07	0.130
rs9789675	2q37.1	233916914	TRPM8	AG	0.494	1.17	0.91–1.51	0.241	0.453	0.63	0.42–0.97	0.034^*
rs9789398	2q37.1	233916979	TRPM8	CT	0.922	1.33	1.01–1.74	0.040^*	0.609	1.59	1.03–2.44	0.034^*
rs1003540	2q37.1	233917239	TRPM8	AG	0.065	0.99	0.82–1.19	0.912	0.394	1.28	0.96–1.70	0.394
rs1004478	2q37.1	233917250	TRPM8	CG	0.06	0.96	0.80–1.16	0.683	0.182	1.21	0.91–1.62	0.194

Note:

P<0.05 indicates statistical significance.

Abbreviations: CI, confidence interval; HWE-P, P-value of Hardy–Weinberg equilibrium; OR, odds ratio; PH, pulmonary hypertension; SNP, single nucleotide polymorphism; TRPM8, transient receptor potential cation channel subfamily M member 8.