Table 1. Characteristics of participants diagnosed with acute or early HIV infection.
INITIAL TESTS* | FOLLOW-UP TESTS | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pt ID | Sex | Marital status | Rapid HIV test | HIV VL | p24 antigen | Genscreen 3rd gen ELISA | W. Blot | LAg avidity | F/U interval (weeks) | F/U Rapid HIV test | F/U HIV VL | F/U LAg avidity | HIV Staging | CD4 count | Pregnancy |
9498 | F | S | - | 509793 | + (10.9) | - (0.05) | n/a | n/a | 10 | + | n/a | Acute | 964 | No | |
9228 | M | S | - | 94 | - (0.3) | - (0.06) | n/a | n/a | 10 | - | 71674 | n/a | Acute | 384 | n/a |
8047 | M | M | - | 1245238 | + (33.8) | - (0.03) | n/a | n/a | 2 | + | n/a | Acute | --- | n/a | |
9218 | F | D | - | 55099 | - (0.4) | + (5.23) | + | 0.143 | 10 | - | 0.103 | Early | 58 | No | |
2066 | F | S | - | 1010 | - (0.5) | + (4.28) | + | 0.058 | 7 | + | 38900 | 0.338 | Early | 752 | No |
8575 | F | S | - | 93079 | + (1.3) | + (5.06) | + | 0.063 | 8 | + | 0.171 | Early | 668 | No | |
7293 | F | S | - | 5078 | - (0.3) | + (4.76) | + | 0.487 | ND | ND | ND | Early | --- | Yes | |
5041 | M | S | - | 22921300 | + (434.1) | + (2.92) | - | 0.073 | ND | ND | ND | Early | --- | n/a | |
9049 | F | S | - | 16848 | - (0.3) | + (5.06) | + | 0.201 | 3 | + | 0.397 | Early | --- | Yes | |
6638 | F | S | - | 195105 | - (0.3) | + (4.45) | + | 0.256 | 6 | + | 0.437 | Early | 457 | Yes | |
261 | M | S | - | 84501600 | + (1383.0) | + (4.06) | - | 0.073 | 9 | + | 1.094 | Early | 386 | n/a | |
6512 | F | S | - | 1763 | - (0.3) | + (4.93) | + | 1.312 | 2 | + | 1938 | 1.111 | Early | 215 | Yes |
6743 | F | S | - | 27364 | - (0.5) | + (4.48) | - | 0.108 | 7 | + | 0.418 | Early | 638 | Yes | |
6582 | F | S | - | 6216 | INSUF | + (4.81) | + | 0.458 | 6 | + | 1.060 | Early | 818 | Yes | |
6727 | F | S | - | 4874 | + (2.6) | + (4.48) | + | 0.234 | 2 | + | 1970 | 0.258 | Early | 706 | Yes |
6737 | F | S | - | 2227 | - (0.3) | + (5.95) | + | 0.746 | ND | ND | ND | ND | Early | --- | Yes |
7084 | F | S | - | 337987200 | + (2884.0) | + (0.17) | - | 0.065 | 4 | + | 0.153 | Early | 411 | No | |
2504 | F | S | - | 37243 | - (0.4) | + (5.95) | + | 1.211 | 2 | + | 1.391 | Early | 287 | Yes | |
3469 | F | S | - | 33274 | + (5.6) | + (5.52) | + | 0.832 | 9 | + | 0.763 | Early | 123 | Yes |
*Initial tests were done from samples obtained at enrolment (i.e after a negative rapid HIV test result). HIV VL tests (including follow-up) were done first to confirm infection, and all the serology tests were done later. Pt ID = participant identity, F = female, M = male or married, S = Single, D = divorced, gen = generation, ELISA = enzyme-linked immunosorbent assay, W. Blot = Western Blot, LAg = limiting antigen, F/U = follow-up, Insuf = insufficient, ND = not done (participant did not come for follow-up), n/a = not applicable, + = positive, - = negative, --- = not available. Units: HIV VL = copies/ml; p24 antigen = cut-off index (COI); Genscreen ELISA = sample cut-off (S/CO); LAg avidity = normalized optical density (OD-n); CD4 count = cells/μl.