Table 2. Frequency of LPC in CD34/CD99 subpopulations.
| Population | Dose | Sample ID | No. engrafted / No. injected | LPC frequency (95% CI) | % FISH + |
|---|---|---|---|---|---|
| Unsorted | 5x106 | 2 | 1/1 | 1: 1.3x105 (0.4x105–3.8x105) | 72–100 |
| 4x106 | 6,9 | 3/3 | |||
| 2x106 | 4,9 | 3/3 | |||
| 1x106 | 2,4,9 | 4/4 | |||
| 5x105 | 3,6,9 | 3/3 | |||
| 1x105 | 3,9 | 1/2 | |||
| 5x104 | 2,4,9 | 1/3 | |||
| 1x104 | 3 | 0/1 | |||
| CD34+/CD99+ | 4x106 | 6 | 1/1 | 1: 3.3x104 (0.1x105–1.1x105) | 66–100 |
| 2x106 | 4 | 1/1 | |||
| 1.5x105 | 9 | 1/1 | |||
| 1x105 | 4,6 | 3/4 | |||
| 3x104 | 2 | 1/1 | |||
| 1x104 | 2 | 1/1 | |||
| 3x103 | 3 | 1/1 | |||
| CD34+/CD99- | 1x105 | 9 | 1/1 | 1: 1.3x103 (0.3x103–5.6x103) | 75–100 |
| 6x104 | 4 | 1/1 | |||
| 5x104 | 2,4 | 2/2 | |||
| 3x104 | 4 | 1/1 | |||
| 1x104 | 3 | 1/1 | |||
| 2.3x103 | 3,6 | 2/2 | |||
| 1x103 | 6 | 0/1 | |||
| CD34-/CD99+ | 2.5x106 | 4 | 1/1 | 1: 5.6x104 (0.2x105–1.6x105) | 70–100 |
| 2.2x106 | 9 | 1/1 | |||
| 1.6x106 | 2 | 1/1 | |||
| 1x106 | 4,9 | 3/3 | |||
| 5x105 | 2 | 1/1 | |||
| 4x105 | 3 | 1/1 | |||
| 3x105 | 6 | 1/1 | |||
| 1x105 | 3,4,6,9 | 3/4 | |||
| 5x104 | 2 | 1/1 | |||
| 2x106 | 2 | 1/1 | 1: 7.4x104 (0.3x105–1.6x105) | 81–100 | |
| 1x106 | 4,9 | 2/2 | |||
| 6x105 | 4 | 1/1 | |||
| CD34-/CD99- | 2x105 | 3 | 1/1 | ||
| 1x105 | 2,3,4,6,9 | 5/7 | |||
| 5x104 | 2,3 | 1/2 |
LPC frequencies calculated using L-Calc Software