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. 2016 Oct 20;10(10):e0005071. doi: 10.1371/journal.pntd.0005071

Fig 4. PLGA-RecE induces a long lasting neutralizing antibody response.

Fig 4

The neutralizing activity of the mice sera was determined by a neutralization assay where DENV is incubated with serially diluted sera and subsequently allowed to infect Vero cells. Neutralizing activity was expressed as the dilution where 50% of the virus was neutralized (Neut50). A) At day 70 post immunization, 1 week post 2nd boost and B) at day 210, 20 weeks post 2nd boost. Statistical differences were determined by one-way ANOVA followed by Tukeys test (p<0.05).