Table 4. Subgroup analysis of summarized hazard ratios reflecting the relationship between survivin and overall survival in cervical cancer.
| Subgroup analysis | No. of | Number of | HR (95%Cls) | P-value |
|---|---|---|---|---|
| studies | patients | |||
| Overall | 3 | 238 | 1.129 (0.597–1.661) | 0 |
| HR estimate | ||||
| HR | 2 | 157 | 1.203 (0.463–1.943) | 0.001 |
| Sur. curve | 1 | 81 | 1.050 (0.285–1.815) | 0.007 |
| Histological type | ||||
| SCC | 1 | 50 | 1.186 (0.060–2.312) | 0.039 |
| ADC & SCC | 2 | 188 | 1.113 (0.509–1.716) | 0 |
| Method | ||||
| IHC | 2 | 188 | 1.203 (0.463–1.943) | 0.007 |
| RT-PCR | 1 | 81 | 1.050 (0.285–1.815) | 0.001 |
| Tumor stage | ||||
| I-II | 1 | 50 | 1.186 (0.060–2.312) | 0.039 |
| I-III | 1 | 81 | 1.050 (0.285–1.815) | 0.007 |
| I-IV | 1 | 107 | 1.216 (0.233–2.199) | 0.015 |
| Cutoff value | ||||
| 5% | 3 | 238 | 1.129 (0.597–1.661) | 0 |