Table 6. Antipsychotic doses when use in combination (n = 287).
| Drug | ATC code | One antipsychotic | Two antipsychotics | Three antipsychotics | Four antipsychotics | ||||
|---|---|---|---|---|---|---|---|---|---|
| N (%) | Mean PDD (mg) | N (%) | Mean PDD (mg) | N (%) | Mean PDD (mg) | N (%) | Mean PDD (mg) | ||
| Amisulpride | N05AL05 | 19 (2.2%) | 315.79 | 22 (4.5%) | 665.91 | 5 (4.7%) | 720.00 | 1 (10%) | 200.00 |
| Aripiprazole | N05AX12 | 181 (21%) | 11.01 | 71 (14.4%) | 16.48 | 9 (8.4%) | 17.22 | 1 (10%) | 25.00 |
| Asenapine | N05AH05 | 59 (6.8%) | 8.01 | 23 (4.7%) | 12.61 | 6 (5.6%) | 9.17 | 0 (0%) | |
| Chlorpromazine | N05AA01 | 1 (0.1%) | 30.00 | 0 (0%) | 2 (1.9%) | 100.00 | 0 (0%) | ||
| Clotiapine | N05AH06 | 5 (0.6%) | 34.00 | 13 (2.6%) | 35.38 | 5 (4.7%) | 48.00 | 1 (10%) | 20.00 |
| Clozapine | N05AH02 | 22 (2.5%) | 248.64 | 40 (8.13%) | 307.13 | 3 (2.8%) | 320.00 | 0 (0%) | |
| Fluphenazine | N05AB02 | 5 (0.6%) | 0.63 | 8 (1.62%) | 1.05 | 3 (2.8%) | 0.89 | 0 (0%) | |
| Haloperidol | N05AD01 | 11 (1.3%) | 3.75 | 11 (2.2%) | 9.34 | 2 (1.9%) | 12.50 | 1 (10%) | 5.00 |
| Levomepromazine | N05AA01 | 10 (1.2%) | 76.00 | 2 (0.4%) | 100.00 | 1 (0.9%) | 100.00 | 0 (0%) | |
| Levosulpiride | N05AL07 | 0 (0%) | 1 (0.2%) | 25.00 | 0 (0%) | 0 (0%) | |||
| Olanzapine | N05AH03 | 102 (11.8) | 8.97 | 37 (7.5%) | 11.96 | 10 (9.3%) | 11.00 | 1 (10%) | 5,00 |
| Paliperidone | N05AX13 | 63 (7.3%) | 6.57 | 31 (6.3%) | 8.81 | 9 (8.4%) | 10.67 | 1 (10%) | 3.00 |
| Long-acting paliperidone | N05AX13 | 118 (13.6%) | 4.00 | 81 (16.5%) | 4.81 | 15 (14%) | 5.48 | 0 (0%) | |
| Perphenazine | N05AB03 | 1 (0.1%) | 8.00 | 0 (0%) | 0 (0%) | 0 (0%) | |||
| Pimozide | N05AG02 | 2 (0.23%) | 2.50 | 1 (0.2%) | 6.00 | 0 (0%) | 0 (0%) | ||
| Quetiapine | N05AH04 | 176 (20.3%) | 158.45 | 79 (16.1%) | 244.78 | 21 (19.6%) | 309.52 | 3 (30%) | 166.66 |
| Risperidone | N05AX08 | 61 (7.0%) | 3.12 | 41 (8.3%° | 5.30 | 7 (6.5%) | 6.50 | 1 (10%) | 3.00 |
| Long-acting risperidone | N05AX08 | 4 (0.5%) | 3.57 | 1 (0.2%) | 3.57 | 0 (0%) | 0 (0%) | ||
| Sertindole | N05AE03 | 0 (0%) | 1 (0.2%) | 4.00 | 0 (0%) | 0 (0%) | |||
| Sulpiride | N05AL01 | 2 (0.2%) | 100.00 | 0 (0%) | 0 (0%) | 0 (0%) | |||
| Tiapride | N05AL03 | 15 (1.7%) | 140.00 | 3 (0.6%) | 150.00 | 1 (0.9%) | 200.00 | 0 (0%) | |
| Ziprasidone | N05AE04 | 4 (0.5%) | 65.00 | 7 (1.4%) | 165.71 | 3 (2.8%) | 133.33 | 0 (0%) | |
| Zuclopenthixol | N05AF05 | 0 (0%) | 1 (0.2%) | 25.00 | 0 (0%) | 0 (0%) | |||
| Zuclopenthixol depot | N05AF05 | 5 (0.6%) | 9.52 | 18 (3.7%) | 11.90 | 5 (4.7%) | 11.43 | 0 (0%) | |
| TOTAL | 866 | 492 | 107 | 10 | |||||