Table 1. Summary of names, PubChem IDs, and the minimal concentrations defined to enhance HSV-2 infection*.
Name | PubChem CID | EC20 (nM) | Inhibitor of |
---|---|---|---|
Trichostatin A | 444732 | 30 | HDAC |
Quisinostat | 11538455 | 30 | HDAC |
CUDC-907 | 54575456 | 30 | HDAC, PI3K |
CUDC-101 | 24756910 | 100 | HDAC |
Givinostat | 9804992 | 100 | HDAC |
HDAC-42 | 6918848 | 100 | HDAC |
Pracinostat | 49855250 | 300 | HDAC |
Scriptaid | 5186 | 300 | HDAC |
Tubastatin A | 57336514 | 3000 | HDAC |
JQ1 | 46907787 | 50 | BET bromodomain |
PFI-1 | 71271629 | 100 | BET bromodomain |
I-BET-762 | 46943432 | 300 | BET bromodomain |
TG101348 | 16722836 | 1000 | BET bromodomain, JAK |
* The concentration that causes a 20% (EC20) reduction in OD readings was given as a minimal concentration required to enhance HSV infection.