Table 2.

Clinical Correlates of Opioid Dose Quartiles

Correlate	Odds Ratio	95% CI	p-value
History of AVN	2.87	1.37-6.02	0.005
25-OHD Concentration	0.59	0.38-0.93	0.024
Total Bilirubin Concentration	0.64	0.42-0.99	0.043

A stepwise ordinal logistic regression analysis was performed of quartiles of daily opioid. The covariates originally placed into the analysis were age, SS/Sbeta0 SCD genotype, history of AVN, 25-OHD levels, AST, and total bilirubin. History of AVN, 25-OHD levels, and total bilirubin remained in the regression model after covariates with P > 0.10 were eliminated from the model in a stepwise manner. The 25-OHD and total bilirubin concentrations were log transformed. N=145.