TABLE 2.

Laboratory values for pre-HU, PBest and recent assessment by deviation from PBest

	Low deviation from PBest (N = 22)			High deviation from PBest (N = 53)			P value
N	Mean	SD	N	Mean	SD
Pre HU
HbF (%)	19	10.7	5.7	41	6.8	4.8	0.009
Hb (gm/dl)	18	8.0	1.0	39	8.0	1.0	0.92
MCV (fl)*	19	83.5	6.2	44	83.9	6.7	0.77
ARC (×109 |−1)	19	266	85	39	352	137	0.02
WBC (×109 |−1)	18	12.5	2.4	39	15.5	5.5	0.03
ANC (×109 |−1)	18	5.4	2.2	39	6.5	4.7	0.81
PBest
HbF (%)	22	21.9	5.1	53	18.5	6.9	0.07
HbF increase: pre-HU to PBest	20	11.4	5.7	43	11.8	5.8	0.94
Hb (gm/dl)	22	9.6	1.4	53	9.0	1.2	0.26
MCV(fl)*	21	99.4	10.3	51	98.9	10.5	0.81
ARC (×109 |−1)	22	162	96	53	172	86	0.52
WBC (×109 |−1)	22	7.6	2.4	53	9.5	4.4	0.04
ANC (×109 |−1)	22	3.7	1.6	52	4.4	3.5	0.72
Recent assessment
HbF (%)	21	19.1	4.5	51	11.4	5.5	<0.001
HbF deviation from PBest (%)	21	11.7	5.3	51	40.1	17.5	<0.001
Hb (gm/dl)	21	9.5	1.2	51	8.6	1.2	0.005
MCV(fl)*	21	99.6	11.6	51	95.0	12.2	0.12
ARC (×109 |−1)	22	194	76	51	276	134	0.02
WBC (×109 |−1)	21	7.7	2.0	51	10.5	3.7	0.002
ANC (×109 |−1)	21	3.6	1.4	51	6.8	13.4	0.02

^*Excludes three patients with HbS-Beta⁰ thalassemia.

Bold font for P values: where significant as P < 0.05.