Skip to main content
. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: Cancer. 2016 Aug 10;122(21):3336–3343. doi: 10.1002/cncr.30197

Table 2.

Treatment response among the matched patients with CML-CP treated with dasatinib and nilotinib.

No. (%) P value
Dasatinib
(N = 87)
Nilotinib
(N = 87)
Response at 3 months
BCR/ABL1 <10% 81 (93) 82 (94) 0.25
Cumulative response at 12 months
MR4.0 42 (48) 44 (51) 0.88
MR4.5 31 (36) 37 (43) 0.34
MMR 67 (77) 74 (85) 0.13
CCyR 82 (94) 82 (94) 0.51
Cumulative response at 36 months
MR4.0 60 (69) 62 (71) 0.73
MR4.5 57 (66) 56 (64) 0.96
MMR 77 (89) 80 (92) 0.17
CCyR 82 (94) 82 (94) 0.51

NOTE: CCyR: Complete cytogenetic response, MMR: Major molecular response (BCR-ABL1/ABL1 ratio ≤ 0.1% by international scale [IS]), MR4.0: Molecular response with 4 log reduction (BCR-ABL1/ABL1 ratio ≤ 0.01% by IS), MR4.5: Molecular response with 4.5 log reduction (BCR-ABL1/ABL1 ratio ≤ 0.0032% by IS)