Table 2.
No. (%) | P value | ||
---|---|---|---|
Dasatinib (N = 87) |
Nilotinib (N = 87) |
||
Response at 3 months | |||
BCR/ABL1 <10% | 81 (93) | 82 (94) | 0.25 |
Cumulative response at 12 months | |||
MR4.0 | 42 (48) | 44 (51) | 0.88 |
MR4.5 | 31 (36) | 37 (43) | 0.34 |
MMR | 67 (77) | 74 (85) | 0.13 |
CCyR | 82 (94) | 82 (94) | 0.51 |
Cumulative response at 36 months | |||
MR4.0 | 60 (69) | 62 (71) | 0.73 |
MR4.5 | 57 (66) | 56 (64) | 0.96 |
MMR | 77 (89) | 80 (92) | 0.17 |
CCyR | 82 (94) | 82 (94) | 0.51 |
NOTE: CCyR: Complete cytogenetic response, MMR: Major molecular response (BCR-ABL1/ABL1 ratio ≤ 0.1% by international scale [IS]), MR4.0: Molecular response with 4 log reduction (BCR-ABL1/ABL1 ratio ≤ 0.01% by IS), MR4.5: Molecular response with 4.5 log reduction (BCR-ABL1/ABL1 ratio ≤ 0.0032% by IS)