Table 1.
| Experimental group ns | ||||
|---|---|---|---|---|
|
| ||||
| Wt | H101R | Q241M | S270H/L277A | |
| Drinking in the dark (DID) | n =10 | 9 | 9 | 10 |
|
| ||||
| DID with lickometer | n =5 | 5 | 9 | 8 |
|
| ||||
| 2-bottle choice DID | n =9 | 8 | - | - |
|
| ||||
| Intermittent access to alcohol (IAA) | n = 11 | 10 | 10 | 10 |
|
| ||||
| Social approach | ||||
| IAA forced abstinence | n = 10 | 9 | 10 | 10 |
| EtOH-naïve | n = 9 | 11 | 9 | 11 |
|
| ||||
| Continuous access to alcohol (CAA) | n = 9 | 8 | 9 | 9 |
|
| ||||
| Ascending concentrations of EtOH (3–20%) | n = 8 | 9 | 9 | 10 |
|
| ||||
| Ascending concentrations of sucrose or quinine | n =8 | 4 | 5 | 7–8& |
&
One mouse euthanized following sucrose testing