Table 3.
Histologic lesion score compared with percentage of neutrophils in the BAL and fecal PCR results
| Lung |
Nasal cavity |
|||||||
| Mouse | Peribronchiolar infiltrates | Perivascular infiltrates | Cellular exudates | Turbinate mucosal infiltrates | Luminal exudates | Foreign bodies | BAL neutrophils (%) | Fecal PCR |
| 1 | — | + | + | ++ | — | — | 20 | + |
| 2 | ++ | ++ | — | ++ | + | + | 5 | + |
| 3 | — | + | — | ++ | + | — | 2 | + |
| 4 | ++ | ++ | — | + | — | — | 20 | + |
| 5 | + | + | — | — | — | — | 2 | — |
| 6 | ++++ | + | — | ++ | ++ to +++ | + | 5 | + |
| 7 | +++ | + | — | ++ to +++ | ++ to +++ | — | 10 | + |
| 8 | ++ | — | +++ | ++ | ++ to +++ | + | 20 | + |
| 9 | — | + | — | ++ | ++ | — | 5 | + |
| 10 | + | + | — | ++ | — | — | 2 | — |
Lesion scores: +, minimal, very mild, or rare; ++, mild; +++, moderate; and ++++, marked.