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Experimental data set from [25] and the catalytic effect of changing from deoxyribose to ribose sugar in T7 RNA polymerase
| WT | Y639F | |||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| KD | kpol | kpol/KD | log Ω | KD | kpol | kpol/KD | log Ω | |
| rATP | 0.1 | 205.0 | 4100.0 | −3.3 | 0.1 | 180.0 | 1914.9 | −0.9 |
| dATP | 3.5 | 7.5 | 2.1 | 0.3 | 60.0 | 222.2 | ||
