Fig. 5.

Effects of L-ZOL and L-ALD on blood counts and spleen. NSG mice were injected with 0.1 μmol L-ZOL or 0.5 μmol L-ALD. After 72 h, the mice were sacrificed. (A) The spleen was removed and weighed. A significant increase in spleen weight could be seen in the case of both L-ZOL and L-ALD. Blood counts were performed by automatic counting. An increase in (B) WBC and (C) % Neutrophils was seen when injected with L-ZOL or L-ALD, while a decrease in (D) % Lymphocytes was observed. (Data were expressed as mean ± SD (n = 10 and n = 5 for spleen weight and blood counts, respectively) *p < 0.05, **p < 0.01, ***p < 0.001. (Student's t-test vs. naive).