Table 1.

Identification of the differentially regulated 2D protein spots of Rv, S-Rv2159c, and As-Rv2159c.

Spot no.	Gene name	Accession no.	Mascot score	No. of matched peptides	Gene index	Theoretical pI/kDa	Expression
GROUP 1: INTERMEDIARY METABOLISM, RESPIRATION
4	Uncharacterised oxidoreductase, GuaB1	Rv1843c	69	1	gi 492067680	6.29/49.93	Absent in AsRv2159c
8	ATP-dependent CLP protease protelytic subunit 2, ClpP2	Rv2460c	74	4	gi 15609597	4.75/23.5	Absent in As-Rv2159c
9, 10, 11	Malate dehydrogenase, Mdh	Rv1240	496	4	gi 489501402	4.39/34.28	More in S-Rv2159c
12	Glycogen accumulation regulator, GarA	Rv1827	457	3	gi 240104237	4.06/17.21	More in S-Rv2159c
GROUP 2: VIRULENCE, DETOXIFICATION AND ADAPTATION
16	Universal stress protein family protein, TB31.7	Rv2623	800	6	gi 685981944	5.55/31.65	Present in AsRv2159c
18	Iron-regulated universal stress protein family protein, TB15.3	Rv1636	243	3	gi 669108828	5.62/15.31	More in AsRv2159c
20, 21	Heat shock protein, HspX	Rv2031c	327	3	gi 801196443	4.75/16.22	Present only in AsRv2159c
GROUP 3: LIPID METABOLISM
7	Fatty acid CoA synthetase, FaD17	Rv3506	79	2	gi 764899599	4.93/53.73	Less in As-Rv2159c
14	3-hydroxyacyl-ACP dehydratase subunit, HadB	Rv0636	83	1	gi 686051919	6.52/14.93	More in S-Rv2159c
GROUP 4: CELL WALL AND CELL PROCESSES
15	Conserved protein with FHA domain, FhaA	Rv0020c	399	3	gi 15607162	4.65/56.88	More in AsRv2159c
GROUP 5: INFORMATION PATHWAY
6	Ribonuclease HII protein, RnhB	Rv2902c	64	3	gi 686045826	10.47/27.64	Absent in AsRv2159c