Table 1.
Patient, clinical, and perioperative characteristics for the operations (n = 428)
| Descr. charact. by leakage | Crude OR for leakage | ||||
|---|---|---|---|---|---|
| No, n = 361 | Yes, n = 67 | OR | 95 % CI | p value | |
| Age (years) | 61.8 (15.1) | 60.7 (15.9) | 0.96 | (0.81, 1.14) | 0.62 |
| Female sex | 47.9 (173) | 35.8 (24) | 0.61 | (0.35, 1.04) | 0.070 |
| Body mass index (kg/m2) | 25.5 (4.8) | 26.2 (4.6) | 1.16 | (0.90, 1.50) | 0.25 |
| Albumin level (g/L) | 40.9 (5.4) | 41.2 (4.1) | 1.06 | (0.80, 1.39) | 0.69 |
| Smoking | 29.1 (91) | 29.8 (17) | 1.04 | (0.56, 1.92) | 0.91 |
| ASA (range 1–4) | 2.0 (0.6) | 2.1 (0.7) | 1.19 | (0.80, 1.76) | 0.39 |
| Malignancy versus benign disease | 50.4 (182) | 65.7 (44) | 1.88 | (1.09, 3.24) | 0.023 |
| Preop. radiotherapy | 9.1 (33) | 9.0 (6) | 0.98 | (0.39, 2.43) | 0.96 |
| Emergency versus elective surgery | 11.9 (43) | 11.9 (8) | 1.00 | (0.45, 2.24) | 0.99 |
| Laparoscopic versus open surgery | 10.5 (38) | 3.0 (2) | 0.26 | (0.06, 1.11) | 0.069 |
| Colorectal versus small bowel anast.* | 73.7 (266) | 85.1 (57) | 2.04 | (1.00, 4.15) | 0.050 |
| Diverting ileostomy | 22.2 (80) | 17.9 (12) | 0.77 | (0.39, 1.50) | 0.44 |
| Use of a vasopressor | 10.3 (37) | 22.4 (15) | 2.52 | (1.29, 4.91) | 0.007 |
| Blood transfusion | 19.1 (69) | 31.3 (21) | 1.93 | (1.08, 3.45) | 0.026 |
| Regular steroid medication | 0.8 (3) | 6.0 (4) | 7.57 | (1.65, 34.6) | 0.009 |
| Medication use | |||||
| No NSAIDs or dexamethasone | 28.3 (102) | 22.4 (15) | 1.00 | ref | |
| Dexamethasone only | 17.5 (63) | 4.5 (3) | 0.32 | (0.09, 1.16) | 0.084 |
| Diclofenac only | 13.0 (47) | 17.9 (12) | 1.74 | (0.75, 4.00) | 0.19 |
| Ketorolac only | 6.4 (23) | 6.0 (4) | 1.18 | (0.36, 3.90) | 0.78 |
| Combinations NSAIDs/dexam. | 34.9 (126) | 49.3 (33) | 1.78 | (0.92, 3.46) | 0.088 |
* Anastomoses with colon, rectum, or the anus in the colorectal group