Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 21;3(5):ENEURO.0130-16.2016. doi: 10.1523/ENEURO.0130-16.2016

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Chenaux et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Figure 7. — Synapse composition is unaltered in SynDIG1-deficient synapses. A, Representative immunoblots of biochemical fractions isolated from WT and SynDIG1 ^β-gal homozygous mutant P14 mouse brain tissue showing levels of GluA1, GluA2, GluN1, GluN2B, PSD-93, PSD-95, synaptophysin (Synapto), SynDIG1, SynDIG4, and PICK-1 present in the S1-, P2-, Syn-, and PSD-enriched fractions. Loading controls are provided by β-actin and β-tubulin immunoreactivity. B–D, Graphs depict the ratio of SynDIG1 ^β-gal homozygous mutant protein relative to WT levels of AMPA receptor subunits (B), NMDA receptor subunits (C), and PSD-93 and PSD-95 (D) in the PSD-enriched fractions. Data are the average of three independent biochemical fractionation experiments; each experiment used four to six mouse brains of each genotype. Error bars represent ±SEM.