Table 2. Identified important deregulated molecules in urine of auto rickshaw drivers (ARD) subjects with respect to office workers (OW).
| No | Observed ppm | Metabolite | HMDB ID | VIP SCORE | Fold change (FC:ARD/OW) | P-value |
|---|---|---|---|---|---|---|
| 1 | 1.272 | L-Isoleucine | HMDB00172 | 1.79 | 5.86 | 0.001 |
| 2 | 1.466 | L-alanine | HMDB00161 | 1.81 | 3.39 | 0.001 |
| 3 | 1.648 | 2-hydroxy valerate | HMDB01863 | 1.43 | 3.67 | 0.004 |
| 4 | 3.985 | Histidine | HMDB00177 | 1.47 | 5.87 | 0.001 |
| 5 | 4.123 | Proline | HMDB00162 | 1.43 | 3.36 | 0.003 |
| 6 | 6.591 | Cisaconitic acid | HMDB00072 | 1.41 | 4.60 | 0.007 |
| 7 | 6.758 | Kynurenine | HMDB00684 | 1.90 | 11.17 | 0.0001 |
| 8 | 6.797 | P-cresol sulfate | HMDB11635 | 1.49 | 3.70 | 0.006 |
| 9 | 6.833 | 4-aminohippuric acid | HMDB01867 | 1.76 | 4.20 | 0.001 |
| 10 | 7.375 | Phenylalanine | HMDB00159 | 1.40 | 3.37 | 0.001 |
| 11 | 7.480 | Benzoic acid | HMDB01870 | 1.70 | 3.31 | 0.001 |
VIP: variable importance in projection.