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. 2016 Oct 21;6:35603. doi: 10.1038/srep35603

Table 1. Univariate analysis for survival outcomes by clinicopathological features.

Variables No. of cases Overall survival
Disease free survival
No. of deaths (%)a 5Y-OSR (%)b Log-rank P No. of events (%)a 5Y-DFSR (%)b Log-rank P
Overall 782 208 (26.6) 62   340 (43.5) 45  
Age (years)
  < 65 383 88 (23.0) 69 2 × 10−3 162 (42.3) 48 0.14
  ≥ 65 399 120 (30.1) 55   178 (44.6) 41  
Sex
 Male 572 173 (30.2) 59 4 × 10−4 261 (45.6) 42 0.10
 Female 210 35 (16.7) 71   79 (37.6) 52  
Smoking status
 Never 232 40 (17.2) 74 3 × 10−4 90 (38.8) 50 0.15
 Ever 550 168 (30.6) 57   250 (45.5) 43  
Diabetes
 No 619 150 (24.2) 66 0.03 259 (41.8) 47 0.19
 Yes 152 51 (33.6) 51   73 (48.0) 36  
Histological types
 SCC 341 103 (30.2) 60 0.17 146 (42.8) 48 0.22
 AC 425 99 (23.3) 63   184 (43.3) 42  
 LCC 16 6 (37.5) 59   10 (62.5) 35  
Pathologic stage
 I 378 59 (15.6) 76 1 × 10−11 107 (28.3) 60 2 × 1015
 II 227 81 (35.7) 52   116 (51.1) 39  
 IIIA 177 68 (38.4) 47   117 (66.1) 20  
Adjuvant therapyc
 No 184 72 (39.6) 49 0.58 102 (56.0) 37 0.36
 Yes 220 77 (34.7) 50   131 (59.0) 25  
Body mass index
  < 25 464 107 (23.1) 65   200 (43.1) 41  
  ≥ 25 183 45 (24.6) 61 0.85 75 (41.0) 46 0.40

Abbreviations: 5Y-OSR, five year-overall survival rate; 5Y-DFSR, five year-disease free survival rate; SCC, squamous cell carcinoma; AC, adenocarcinoma; LCC, large cell carcinoma.

aRow percentage.

bFive year-overall survival rate and five year-disease free survival rate, proportion of survival derived from Kaplan-Meier analysis.

cIn pathologic stages II + IIIA: 182 cases received adjuvant chemotherapy alone, 11 cases received adjuvant radiotherapy alone, and 27 cases received both chemotherapy and radiotherapy.