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. 2016 Oct 21;6:35771. doi: 10.1038/srep35771

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Copyright © 2016, The Author(s)

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(A) The tumour diameters were measured and used to calculate the tumour volumes. The HepG2 xenograft-bearing mice were intravenously injected with 2.5, 5, 10 and 50 mg/kg 8n for 20 days. (B) After 20 days, mice were sacrificed and the individual tumours were weighed. *p < 0.05, *p < 0.01; Student’s t-test (n = 6). (C) The tumour diameters were measured and used to calculate the tumour volumes. The HepG2 xenograft-bearing mice were orally administered 50 mg/kg 8n, 50 mg/kg DDO-6101 or 10 mg/kg 5-FU for 20 days.