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. 2016 Oct 21;6:35691. doi: 10.1038/srep35691

Table 1. Demographic data and receptor gene expression of patients and healthy controls.

  Patients (n = 124) Controls (n = 57) t/χ2 p
Age (years) 36.65 ± 9.74 36.19 ± 10.60 −0.43 0.67
Male 84 (67.74%) 36 (63.16%) 0.37 0.55
Education (years) 9.74 ± 1.75 10.19 ± 1.96 −1.26 0.22
Age of initial use (years) 31.87 ± 10.77      
Duration of use (months) 22.21 ± 31.73      
Average dose one time (g) 0.44 ± 0.39      
GRIA2 (pg/ml) 32.58 ± 10.46 23.56 ± 9.68 5.18 0.00
GABRA1 (ng/ml) 1.09 ± 0.79 1.57 ± 0.93 −2.49 0.02

Patients: methamphetamine-use disorder patients; GRIA2: glutamate receptor, ionotropic, AMPA 2; GABRA1: gamma-aminobutyric acid type A receptor alpha1 subunit.