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. 2011 Jun 13;29(21):2852–2858. doi: 10.1200/JCO.2010.33.4714

Table A2.

Multivariate Analysis of Predictors for LRR and OS in T1-2N0 Group Treated With MRM Compared With BCT

Variable LRR
OS
HR 95% CI P HR 95% CI P
Tumor grade
    1-2 1 1
    3 1.13 0.43 to 2.96 .79 0.82 0.42 to 1.6 .56
LVI
    Negative 1 1
    Positive 1.17 0.48 to 2.87 .73 1.9 1.16 to 4.08 .0155
Locoregional therapy
    BCT 1 1
    MRM 2.53 1.12 to 5.75 .0264 1.13 0.63 to 2.02 .68
Adjuvant chemotherapy
    No 1 1
    Yes 0.51 0.24 to 1.06 .07 0.34 0.19 to 0.60 < .001

Abbreviations: BCT, breast-conserving therapy; HR, hazard ratio; LRR, locoregional recurrence; LVI, lymphovascular invasion; MRM, modified radical mastectomy; OS, overall survival; RT, radiation therapy.