Table A2.
Multivariate Analysis of Predictors for LRR and OS in T1-2N0 Group Treated With MRM Compared With BCT
Variable | LRR |
OS |
||||
---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Tumor grade | ||||||
1-2 | 1 | 1 | ||||
3 | 1.13 | 0.43 to 2.96 | .79 | 0.82 | 0.42 to 1.6 | .56 |
LVI | ||||||
Negative | 1 | 1 | ||||
Positive | 1.17 | 0.48 to 2.87 | .73 | 1.9 | 1.16 to 4.08 | .0155 |
Locoregional therapy | ||||||
BCT | 1 | 1 | ||||
MRM | 2.53 | 1.12 to 5.75 | .0264 | 1.13 | 0.63 to 2.02 | .68 |
Adjuvant chemotherapy | ||||||
No | 1 | 1 | ||||
Yes | 0.51 | 0.24 to 1.06 | .07 | 0.34 | 0.19 to 0.60 | < .001 |
Abbreviations: BCT, breast-conserving therapy; HR, hazard ratio; LRR, locoregional recurrence; LVI, lymphovascular invasion; MRM, modified radical mastectomy; OS, overall survival; RT, radiation therapy.