Table 1.

Proposed search strategy for PubMed and EMBASE

Database	Search query
PubMed	(“Liver cirrhosis”[Mesh] OR cirrho*[ti] OR “hepatic impairment”[ti] OR “liver impairment”[ti] OR “hepatic dysfunction”[ti] OR “liver dysfunction”[ti] OR “hepatic insufficiency”[ti] OR “liver insufficiency”[ti]) AND (“X”[Mesh] OR “X”[tiab]) AND “humans”[MeSH Terms]
EMBASE	‘liver cirrhosis’/exp OR cirrho*:ti OR ‘hepatic impairment’:ti OR ‘liver impairment’:ti OR ‘hepatic dysfunction’:ti OR ‘liver dysfunction’:ti OR ‘hepatic insufficiency’:ti OR ‘liver insufficiency’:ti AND (‘X'/exp OR ‘X’:ab,ti) AND [humans]/lim

X, name of drug to be evaluated.