Table 1.
Antimicrobial susceptibilities (mg/L) and FICIs.
| Isolate | MIC (PEN)MB | MIC (PEN)E | MIC (GEN)MB | FICIsMB |
|---|---|---|---|---|
| GBS-PJI | 0.03 (0.016–0.04) | 0.064 (0.047–0.064) | 23.4 (15.6–31.25) | 1.4 (0.9–1.5) |
| GBS-IE | 0.04 (0.016–0.04) | 0.064 (0.032–0.064) | 15.6 (7.8–15.6) | 1.4 (0.8–2.3) |
| NEM316 | 0.04 (0.032–0.04) | 0.064 (0.047–0.064) | 15.6 (7.8–15.6) | 0.8 (0.7–1) |
| GBS-Col | 0.02 (0.016–0.04) | 0.064 (0.047–0.064) | 7.8 (7.8–15.6) | 2 (1.5–2) |
| GBS-HLGR | 0.04 (0.016–0.04) | 0.047 (0.047–0.047) | >1024 | 2 (2–2) |
All measurements were repeated three or more times. MIC results are presented as median and range of results in parenthesis. E, Etest; MB, microbroth dilution; PEN, penicillin; GEN, gentamicin; FICI, fractional inhibitory concentration index; GBS-PJI, group B Streptococcus isolated from a periprosthetic joint infection; GBS-IE, group B Streptococcus isolated from infective endocarditis; GBS-Col, group B Streptococcus isolated from colonized women; GBS-HLGR, group B Streptococcus displaying high level gentamicin resistance.