Table 1.
Various other factors influence transplanted organ prognoses and require further investigation.
| Risk factors | Out come | |||
|---|---|---|---|---|
| Study size | Organ | ABMR | Graft loss | Reference |
| 226 | Kidney | Highly sensitized patients | ABMR-positive | (147) |
| DSA relative intensity scores greater than 17 | Thrombotic microangiopathy (TMA) positive | |||
| Presence of both class I and II DSAs at transplant | Induction with intravenous immunoglobulin and rituximab | |||
| 62 | C1q-positive | C1q-positive | (148) | |
| Both of DSA- and C1q-positive | ||||
| Transplant glomerulopathy | ||||
| Decline of eGFR | ||||
| 1016 | Complement-binding DSA DSA-positive | Complement-binding DSA | (149) | |
| DSA-positive | ||||
| 1307 | Subclinical ABMR | (150) | ||
| Subclinical TCMR | ||||
| 1365 | TCMR | TCMR diagnosed after the first year post-transplant | (151) | |
| Chronic histological injury | ||||
| Transplant glomerulopathy | ||||
| 67 (grafts) | Late aABMR | (152) | ||
| 885 | Capillary C4d-positive | (153) | ||
| 1054 | TCMR | Higher glomerulitis scores | (154) | |
| Higher C4d staining scores | ||||
| 1 | Plasma cell-rich rejection (PCRR) with ABMR | (155) | ||
| 237 | DSA-positive preformed DSA-positive | DSA-positive | (7) | |
| AMR | ||||
| DSA-positive/CXM-positive | ||||
| 234 | Microcirculation inflammation | (4) | ||
| 274 | C1q-fixing DSAs | (140) | ||
| 152 | Pancreas-kidney | De novo DSA-positive | (67) | |
| 439 | Pancreas | Elevated DSA | (156) | |
| Preformed DSA-positive | ||||
| 2631 | Liver | Preformed class II DSAs positive MFI ≧5000 | (19) | |
| 1270 | Preformed C1q-fixing class II DSA | IgG3 DSA-positive | (157) | |
| De novo IgG3 DSA | ||||
| 749 | De novo DSA development | (158) | ||
| 15 | Heart | SAB-C1q-positive DSA CDC-XM-positive | (9) | |
| 243 | De novo DSA-positive | (159) | ||
| Persistent DSA | (160) | |||
| 44 | Lung | DSA-positive | HLA-DQ DSA (>10,000) | (71) |
| 60 | ||||
| 546 | Early anti-HLA class II DSA | (72) | ||
| Pre-operative HLA antibodies | ||||
| Retransplantation | ||||
| Postoperative PGD | ||||
| 79 | Intestine | De novo DSA development early after transplant | (161) | |
| 291 | DSA-positive | DSA-positive | (162) | |