Table 2.

The use of ADSCs together with various scaffolds in in vivo animal models

Animal model	Scaffold	Result	Reference
hADSCs subcutaneously in BalB/c nude mice	polylacticcoglycolic acid (PLGA) with bone forming peptide and polydopamine film	superior ectopic bone formation	[55]
hADSCs mixed with porcine atelocollagen in BalB/c nude mice calvarium	nano hydroxyapatite	osteogenesis of transplanted ADSCs and thick new bone formation	[56]
Mouse ADSCs in femoral segmental critical-sized defect in mouse	sterile cancellous bone	new bone formation not only at the bony edges but also inside the scaffold	[57]
Rat miR-135 transduced ADSCs in critical-sized calvarial defect in rats	poly(sebacoyl diglyceride)	new bone formation	[58]
Rat ADSCs in rotator cuff model in rat	multilayered PLGA nanofibers with fibrin matrix with BMP2	impaired tendon to bone healing with BMP2	[59]