Figure 2.

Twenty-four-hour time-kill study. Studies were performed to determine the pharmacodynamic activity of antimicrobial agents. Our patient's Proteus mirabilis blood isolate was grown with antibiotics to parallel clinical dosing (concentration detailed in text) and bacterial survival compared with control growth. Ceftriaxone, combined with gentamicin, at 1and 5 mg/kg equivalents, demonstrated the most efficient synergistic bactericidal activity.