Table 2.

Estradiol and carrier protein concentrations

	Control subjects vs. sepsis patients			Sepsis, survivors vs. nonsurvivors
Variable	Controls (n = 51)	Sepsis (n = 131)	p Value	Survivors (n = 98)	Nonsurvivors (n = 33)	p Value
Total estradiol, pM	115 (88–166)	275 (112–916)	<0.01	222 (100–814)	512 (276–1040)	0.01
Albumin-bound estradiol, pM	97 (76–139)	199 (74–637)	<0.01	156 (66–538)	278 (154–855)	0.04
Free estradiol, pM	3 (2–4)	10 (4–46)	<0.01	8 (4–28)	23 (10–73)	<0.01
Bioavailable estradiol, pM	100 (78–142)	211 (78–675)	<0.01	167 (70–566)	312 (164–918)	0.04
Albumin, g/dl	5.24 (4.61–5.71)	2.67 (2.06–3.49)	<0.01	3.00 (2.30–3.74)	2.06 (1.72–2.63)	<0.01
SHBG, nM	9.52 (4.13–22.06)	19.00 (10.50–32.80)	<0.01	19.00 (11.20–32.50)	17.41 (7.92–34.19)	0.70

SHBG Sex hormone-binding globulin

Values are given as median (interquartile range)