Table 1.
Patient characteristics
| Lesion number | Location | Histology | Previous RT | TBR max | TBR mean | TAC | TTP | Months between RT and PET | Final diagnosis | Diagnostic determinant | Follow up (months) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R parietal | NSCLC | SRS | 1.5 | 1.4 | n.a. | n.a. | 1.9 | Radiation induced lesion | Follow up | 9.4 |
| 2 | L insular | Malignant melanoma | SBT | 3.4 | 2.3 | Decreasing | 12.5 | 2.1 | Tumor | Follow up | 14.8 |
| 3 | L insular | Malignant melanoma | SRS | 3.4 | 2.3 | Increasing | 35 | 2.2 | Tumor | Histology | 4.2 |
| 4 | L parietooccipital | NSCLC | SBT | 2.1 | 1.9 | Decreasing | 25 | 2.4 | Tumor | Histology | 29.9 |
| 5 | L occipital | NSCLC | SBT | 2.8 | 2.1 | Increasing | 35 | 2.5 | Radiation induced lesion | Follow up | 6.7 |
| 6 | L frontal | Malignant melanoma | SBT | 4.1 | 2.5 | Increasing | 35 | 2.6 | Tumor | Follow up | 4.6 |
| 7 | L parietal | CUP | SRS | 1.8 | 1.8 | Increasing | 35 | 3 | Radiation induced lesion | Follow up | 4.9 |
| 8 | L pontine | Breast cancer | SRS | 1.5 | 1.3 | n.a. | n.a. | 4.6 | Radiation induced lesion | Follow up | 30.9 |
| 9 | R temporal | Malignant melanoma | SRS | 2.1 | 1.9 | Increasing | 17.5 | 4.7 | Radiation induced lesion | Follow up | 16 |
| 10 | L frontal | Malignant melanoma | SRS | 2.0 | 1.9 | Decreasing | 17.5 | 4.7 | Tumor | Histology | 16 |
| 11 | L cerebellar | Breast cancer | SRS | 1.7 | 1.2 | Increasing | 35 | 4.7 | Radiation induced lesion | Follow up | 30.9 |
| 12 | R parietal | Malignant melanoma | SRS | 1.4 | 1.0 | n.a. | n.a. | 4.8 | Radiation induced lesion | Follow up | 6.8 |
| 13 | R parietal | NSCLC | SRS | 1.5 | 1.4 | n.a. | n.a. | 5.3 | Tumor | Histology | 9.4 |
| 14 | L insular | Malignant melanoma | SBT | 3.2 | 2.3 | Decreasing | 17.5 | 5.4 | Radiation induced lesion | Follow up | 14.8 |
| 15 | R temporal | NSCLC | SRS | 1.5 | 1.3 | n.a. | n.a. | 6 | Radiation induced lesion | Follow up | 13.6 |
| 16 | L occipital | NSCLC | SRS | 2.8 | 2.1 | Decreasing | 12.5 | 6 | Tumor | Histology | 13.6 |
| 17 | L temporal | Malignant melanoma | SRS | 2.9 | 2.1 | Increasing | 35 | 6 | Radiation induced lesion | Follow up | 33.8 |
| 18** | R frontal | Malignant melanoma | SRS | 1.4 | 1.3 | Increasing | 35 | 8 | Radiation induced lesion | Follow up | 42.5 |
| 19 | R cerebellar | Gastrointestinal cancer | SRS | 2.3 | 2.0 | Decreasing | 12.5 | 8.5 | Tumor | Histology | 18 |
| 20 | L frontal | NSCLC | SRS | 1.9 | 1.8 | Increasing | 35 | 8.6 | Radiation induced lesion | Histology | 35.1 |
| 21 | R frontal | NSCLC | SRS | 1.6 | 1.4 | Increasing | 35 | 8.7 | Radiation induced lesion | Histology | 43.1 |
| 22 | L frontal | NSCLC | SRS | 1.2 | 1.0 | n.a. | n.a. | 8.7 | Radiation induced lesion | Follow up | 43.1 |
| 23 | L frontal | Malignant melanoma | SRS | 2.4 | 2.0 | Decreasing | 25 | 9.1 | Tumor | Histology | 22.2 |
| 24 | R frontal | Gastrointestinal cancer | SRS | 2.0 | 1.9 | Increasing | 25 | 9.3 | Radiation induced lesion | Histology | 17.1 |
| 25 | R frontal | NSCLC | SRS | 2.0 | 1.9 | Decreasing | 25 | 9.3 | Radiation induced lesion | Histology | 23.8 |
| 26 | R temporal | NSCLC | SRS | 1.5 | 1.1 | n.a. | n.a. | 9.4 | Radiation induced lesion | Follow up | 13.6 |
| 27 | L insular | Malignant melanoma | SBT | 3.5 | 2.4 | Decreasing | 7.5 | 10.5 | Radiation induced lesion | Follow up | 14.8 |
| 28 | L parietal | Malignant melanoma | SBT | 2.5 | 2.1 | Decreasing | 12.5 | 12.3 | Tumor | Histology | 14.5 |
| 29 | R temporal | Malignant melanoma | SRS | 1.5 | 1.2 | n.a. | n.a. | 14 | Radiation induced lesion | Follow up | 16 |
| 30* | L frontal | Malignant melanoma | SRS | 3.5 | 2.3 | Decreasing | 7.5 | 14 | Tumor | Histology | 16 |
| 31 | L insular | Malignant melanoma | SBT | 3.5 | 2.4 | Decreasing | 12.5 | 14.7 | Radiation induced lesion | Follow up | 14.8 |
| 32 | R occipital | Breast cancer | SRS | 1.8 | 1.8 | Increasing | 35 | 15 | Radiation induced lesion | Follow up | 79.2 |
| 33 | R frontal | Breast cancer | SRS | 2.0 | 1.9 | Increasing | 35 | 15 | Radiation induced lesion | Follow up | 79.2 |
| 34 | L cerebellar | Breast cancer | SRS | 1.8 | 1.7 | Increasing | 35 | 15 | Radiation induced lesion | Follow up | 79.2 |
| 35 | L occipital | NSCLC | SRS | 3.0 | 2.1 | Decreasing | 4 | 15.8 | Tumor | Histology | 25.1 |
| 36 | L frontal | Malignant melanoma | SRS | 2.1 | 1.9 | Increasing | 35 | 18.2 | Radiation induced lesion | Follow up | 24.1 |
| 37 | R frontal | NSCLC | SRS | 3.0 | 2.2 | Decreasing | 12.5 | 18.6 | Tumor | Follow up | 23.8 |
| 38 | R frontal | Malignant melanoma | SRS | 3.5 | 2.2 | Increasing | 25 | 19.8 | Tumor | Follow up | 42.5 |
| 39 | R frontal | Malignant melanoma | SRS | 2.2 | 2.0 | Decreasing | 4 | 19.8 | Tumor | Follow up | 42.5 |
| 40 | L cerebellar | Breast cancer | SRS | 3.8 | 2.7 | Increasing | 35 | 19.9 | Tumor | Histology | 30.9 |
| 41 | L pontine | Breast cancer | SRS | 4.3 | 2.8 | Decreasing | 25 | 19.9 | Tumor | Histology | 30,9 |
| 42 | L frontal | Malignant melanoma | SRS | 2.0 | 1.9 | Decreasing | 17.5 | 20.3 | Radiation induced lesion | Follow up | 24.1 |
| 43 | L frontal | Malignant melanoma | SRS | 2.4 | 2.0 | Decreasing | 25 | 20.8 | Tumor | Histology | 22.2 |
| 44 | R frontal | NSCLC | SRS | 3.9 | 2.6 | Decreasing | 12.5 | 22.6 | Tumor | Follow up | 23.8 |
| 45 | R frontal | Breast cancer | SRS | 1.5 | 1.4 | Decreasing | 25 | 22.9 | Radiation induced lesion | Follow up | 33 |
| 46 | L cerebellar | Breast cancer | SRS | 2.4 | 2.0 | Decreasing | 17.5 | 22.9 | Tumor | Histology | 33 |
| 47 | R cerebellar | NSCLC | SRS | 2.6 | 2.0 | Decreasing | 17.5 | 23.5 | Radiation induced lesion | Histology | 33.6 |
| 48 | R frontal | Malignant melanoma | SRS | 1.4 | 1.3 | Decreasing | 4 | 28.4 | Radiation induced lesion | Follow up | 42.5 |
| 49 | L parietal | NSCLC | SRS | 1.7 | 1.5 | Increasing | 35 | 42.2 | Radiation induced lesion | Follow up | 51.5 |
| 50 | R cerebellar | Renal cell carcinoma | SRS | 2.9 | 2.1 | Decreasing | 17.5 | 90.3 | Tumor | Histology | 99.1 |