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. 2016 Oct 20;16:814. doi: 10.1186/s12885-016-2847-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — RNAseq analysis reveals both overlapping and non-overlapping gene expression patterns in MCF-7/AC-1 xenografts. a Venn Diagram of the overlapping and unique number of genes according to treatment cohort(s). b Heatmap depicting the most significantly up (red) and down (green) regulated genes in LET + MK-8669 + MK-0646-treated tumors compared to the remaining treatment cohorts. Color bar indicates log-fold expression change compared to control tumors