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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Psychopharmacology (Berl). 2016 Mar 30;233(10):1845–1866. doi: 10.1007/s00213-016-4244-7

Figure 3. Neuroanatomical probe placements and neurochemical effects of WIN55,212-2 self-administration in Sprague-Dawley rats.

Figure 3

Top Panel. Schematic drawings showing the location of microdialysis probes in the nucleus accumbens shell or core in rats self-administering WIN55,212-2 (12.5 µg/kg/infusion). Bottom panel shows the time course of changes from basal DA levels in dialysates from the shell and core of the nucleus accumbens in rats during 4 weeks (12 sessions) of WIN55,212-2 self-administration. Modified from Lecca et al 2006. See text and the original article for more details about experimental procedures and results.