Table 1.

Program inputs (with notation from Coffey and Muller 2001).

GLUMIP	Symbol	Dimensions	Description
Required design parameters:
ESSENCEX	Es (X+)	g × q	Essence design matrix
ALPHAT	α t	1 × 1	Target type I error rate
POWERT	Pt	1 × 1	Target power
C	C	a × q	Contrast matrix
BETA_PLN	β *	q × 1	Primary parameters for power calculations
SIGMAO	${\sigma }_0^2$	1 × 1	Planning variance estimate
Required fixed parameters:
GAMLIST	γ	1 × h	List of gamma values: $\gamma ={\sigma }^2∕{\sigma }_0^2$
BETA_ALT	β	q × 1	True primary parameters
Required internal pilot rules:
N1	n 1	1 × 1	Internal pilot sample size
NPLUSMIN	n +,min	1 × 1	Minimum final sample size
RULE		1 × 1	Sample size re-estimation rule
TEST		1 × 1	Testing method
Optional inputs:
WEIGHTS		g × 1	Weights for rows of Es (X+) per replication
NPLUSMAX	n +,max	1 × 1	Maximum final sample size
ROUND		1 × 1	Places to round N+ pdf relative to αt (1-10)