Table 1.
Pegfilgrastim group (n = 53) | Filgrastim group (n = 54) | |||
---|---|---|---|---|
n | % | n | % | |
Sex | ||||
Male | 35 | 66·0 | 31 | 57·4 |
Female | 18 | 34·0 | 23 | 42·6 |
Age (years) | ||||
Median (Range) | 61·0 (28–74) | 60·5 (24–79) | ||
Body weight (kg) | ||||
Mean (SD) | 60·85 (11·01) | 61·94 (15·29) | ||
<60 kg | 25 | 47·2 | 27 | 50·0 |
≥60 kg | 28 | 52·8 | 27 | 50·0 |
Body surface area (m2) | ||||
Mean (SD) | 1·66 (0·18) | 1·66 (0·23) | ||
Primary disease | ||||
Non‐Hodgkin lymphoma | 50 | 94·3 | 50 | 92·6 |
B‐cell lymphoma | ||||
Diffuse large B‐cell lymphoma | 30 | 56·6 | 26 | 48·1 |
Follicular lymphoma | 7 | 13·2 | 9 | 16·7 |
Mantle cell lymphoma | 2 | 3·8 | 2 | 3·7 |
Nodal marginal zone B‐cell lymphoma | 1 | 1·9 | 0 | 0 |
Primary mediastinal large B‐cell lymphoma | 0 | 0 | 1 | 1·9 |
T/NK‐cell lymphoma | ||||
Peripheral T‐cell lymphoma, unspecified | 5 | 9·4 | 7 | 13·0 |
Anaplastic large cell lymphoma | 2 | 3·8 | 3 | 5·6 |
Other | 3 | 5·7 | 2 | 3·7 |
Hodgkin lymphoma | 3 | 5·7 | 4 | 7·4 |
Clinical stage | ||||
I | 4 | 7·5 | 1 | 1·9 |
II | 7 | 13·2 | 20 | 37·0 |
III | 15 | 28·3 | 13 | 24·1 |
IV | 27 | 50·9 | 20 | 37·0 |
Bone marrow involvement | ||||
+ | 6 | 11·3 | 5 | 9·3 |
− | 46 | 86·8 | 47 | 87·0 |
Unknown | 1 | 1·9 | 2 | 3·7 |
Other malignancy | ||||
Absent | 53 | 100·0 | 53 | 98·1 |
Present | 0 | 0 | 1 | 1·9 |
Operation prior to primary disease | ||||
No | 48 | 90·6 | 53 | 98·1 |
Yes | 5 | 9·4 | 1 | 1·9 |
Radiotherapy prior to primary disease | ||||
No | 46 | 86·8 | 48 | 88·9 |
Yes | 7 | 13·2 | 6 | 11·1 |
Chemotherapy prior to primary disease | ||||
No | 1 | 1·9 | 0 | 0 |
Yes | 52 | 98·1 | 54 | 100·0 |