. 2016 Apr 26;94(8):693–701. doi: 10.1002/jnr.23749

Table 2.

Phenotypic Characterization of Bregs in Human Neuroimmunologic Disorders

Neuroimmunologic disorders	Changes in various phenotype Bregs	References
MS	↑CD19⁺CD25⁺ Bregs in relapsing MS vs. remitting MS	Knippenberg et al., 2011; de Andres et al., 2014; Michel et al., 2014
	↑CD19⁺CD25⁺ Bregs in remitting MS vs. HC
	–CD19⁺CD24^hiCD38^hi Bregs in MS vs. HC
	↓CD19⁺IL10⁺ Bregs in MS vs. HC
NMO	↓CD19⁺CD24^hiCD38^hi Bregs in NMO vs. MS	Quan et al., 2013; Yang et al., 2015
	↓CD19⁺CD24^hiCD38^hi Bregs in NMO vs. HC
	↓CD19⁺CD5⁺CD1d^hi Bregs in NMO vs. MS
	↓CD19⁺CD5⁺CD1d^hi Bregs in NMO vs. MS
MG	↓CD19⁺CD24^hiCD38^hi Bregs in MG vs. HC	Sun et al., 2014
MG	↓CD19⁺CD5⁺CD1d^hi Bregs in MG vs. HC	Sun et al., 2014