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Differences in overall survival by (A) presence of extramedullary disease, (B) presence of splenic involvement, (C) presence of CNS involvement, and (D) combination of cytogenetic risk and presence of extramedullary involvement. P values are from the log-rank test. Cyto, cytogenetic; EMD, extramedullary disease; fav, favorable; intermed, intermediate; pts, patients; unfav, unfavorable.
